Assessing the impact of changes in the management of Ulcerative Colitis patients who have an incomplete response to TNFa Therapy

Challenge

Lack of treatment options resulted in UC patients left on TNFa with dose intensification, adjunct steroids or other therapy combinations despite failing to achieve remission.

How has the approval of novel therapies changed practice and patient outcomes?

Solution

Using a representative study population with detailed clinical data from gastroenterology practices, assessed treatment patterns and patient and clinical characteristics associated with switching.

UC patients with deep clinical data and clinical notes


UC patients treated with advanced therapies