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AI Applications for Clinical Development: From Identifying Patients to Amplifying Trial Endpoints

Inside Precision Medicine Published Online: August 18, 2022 Read the Full Article >> Artificial intelligence (AI) has promised major breakthroughs in clinical development success. While the hype has sometimes seemed overblown, AI is starting to deliver on those promises through real-world impact. AI is not a silver bullet for all challenges, but in specific applications,[…]

Validation of a machine learning approach to estimate expanded disability status scale scores for multiple sclerosis

Sage Journals Published June 22, 2022 Read the Full Manuscript>>  Abstract Background Disability assessment using the Expanded Disability Status Scale (EDSS) is important to inform treatment decisions and monitor the progression of multiple sclerosis. Yet, EDSS scores are documented infrequently in electronic medical records. Objective To validate a machine learning model to estimate EDSS scores[…]

Understanding Heart Failure through the Real-World Data Lens

Pharmaceutical Executive Online Read the Full Article >> An estimated 64 million people suffer from heart failure (HF) globally. Americans have a 20% lifetime risk of developing HF. Although recent progress in the development of new treatments has led to a modest decrease in morbidity and mortality, mortality for heart failure patients remains unacceptably high[…]

A new approach for post-marketing safety studies

BioPharma Dive Online April 4, 2022 Read the Full Article >>   The large quantity of digitized healthcare data in the U.S., combined with advancements in data collection and processing technologies, present an enormous opportunity to shift dramatically how post-marketing safety studies can and should be conducted. The Traditional Approach Post-marketing safety studies are a[…]

Real-World Data Delivers Dose of Hope for Mental Health in the U.S.

Pharmaceutical Executive Online Published: March 15, 2022 Read the Full Article >> If you were asked which health care conditions rank as the highest in both unmet need and in cost, which would you choose? Would it be cancer or heart disease? While those conditions certainly place in both categories, mental health outranks them in[…]