Gastroenterology
Addressing gaps in care and insights
Gastroenterology disorders affect up to 11% of the U.S. population. Irritable Bowel Diseases (IBD), such as crohn’s disease and ulcerative colitis, are lifelong conditions that cause chronic inflammation in the intestines, leading to pain and swelling in patients. Other conditions like NASH, are difficult to diagnose and have few treatment options.
Gastroenterology conditions are complex. Accessing data shouldn’t be.
Understanding the complexities of these systemic inflammatory diseases, and the factors that affect response to treatments, drives our focus on bringing a dynamic new approach to real world evidence generation to healthcare stakeholders.
Meet the data network focused on Gastroenterology disorders
A comprehensive view of the patient journey from clinical development to the clinic
Bringing new treatments to market and delivering more precise care is challenging enough. Finding the data to empower your programs shouldn’t be. That’s why OM1 built the largest gastroenterology network in the U.S — rich with longitudinal clinical data and ready for addressing your most urgent questions.
26IDNs |
2,000+GI Specialists |
• Crohn’s Disease |
Sample conditions*
Every condition presents its own unique challenges and opportunities. Select one of our sample datasets above to explore some of the features.
CD patients with deep clinical data including specialist’s notes and many with extracted and calculated CDAI
7 yrs
Mean follow-up
&
Extracted and Calculated CDAI scores
UC patients with deep clinical data and many with extracted and calculated Mayo scores
7 yrs
Mean follow-up
&
Extracted and Calculated Mayo scores
NASH patients with deep clinical data including many with liver biopsy results
7.0 yrs
Mean follow-up
*Data counts as of Q3 2022 ©OM1 Gastroenterology Data Specialty Area
From evidence to insights
USE CASE
Assessing the impact of changes in the management of Ulcerative Colitis patients who have an incomplete response to TNFa Therapy
Lack of treatment options resulted in UC patients left on TNFa with dose intensification, adjunct steroids or other therapy combinations despite failing to achieve remission. How has the approval of novel therapies changed practice and patient outcomes?
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USE CASE
Leveraging Observed and Calculated CDAI Scores in Patients with Crohn’s Disease to Understand Response to Therapy
The Crohn’s Disease Activity Index (CDAI) is used in clinical practice and randomized control trials (RCTs) to assess the patient’s clinical status, to select appropriate therapies, and to assess the response to treatments. Despite the value of the CDAI score, it is not frequently assessed in clinical setting.
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USE CASE
Identify under-and un-diagnosed NASH patients with deep clinical data and advanced AI
Identification of both probable and confirmed non-alcoholic fatty liver disease (NAFLD) and NASH is hampered by asymptomatic disease, under-diagnosis in routine care, lack of condition-specific treatments and poor billing code specificity.
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Meet our Clinician Lead
Gary Curhan, MD, ScD is the Chief Medical Officer of OM1, Inc. He is a practicing nephrologist in Boston. Dr. Curhan has published widely on the epidemiology of many medical conditions including cardiovascular disease, hypertension, kidney stones, gout, hearing loss and others. His research in several large cohort studies, including the Nurses’ Health Studies and the Health Professionals Follow-Up Study, focuses on the prevention of common diseases by investigating scientifically and clinically important questions and exploring the role of modifiable factors and has been supported continuously for over 25 years by the National Institutes of Health. He was the Editor-in-Chief of the Clinical Journal of the American Society of Nephrology, a leading nephrology journal. He has served on many national and international advisory committees, including the National Institutes of Health. He has mentored numerous individuals, many of whom now hold leadership positions at major academic institutions and public companies.
Dr. Curhan is a graduate of Brown University, Harvard Medical School and Harvard School of Public Health. Prior to joining OM1, he was a Professor of Medicine at Harvard Medical School and Professor of Epidemiology at Harvard School of Public Health.