Gastroenterology

Addressing gaps in care and insights

Gastroenterology disorders affect up to 11% of the U.S. population. Inflammatory Bowel Diseases (IBD), such as crohn’s disease and ulcerative colitis, are lifelong conditions that cause chronic inflammation in the intestines, leading to pain and swelling in patients. Other conditions like MASH* (metabolic dysfunction-associated steatohepatitis), are difficult to diagnose and have few treatment options.

*Formerly known as NASH

Gastroenterology conditions are complex. Accessing data shouldn’t be.

Understanding the complexities of these systemic inflammatory diseases, and the factors that affect response to treatments, drives our focus on bringing a dynamic new approach to real world evidence generation to healthcare stakeholders.

Meet the data network focused on Gastroenterology disorders

A comprehensive view of the patient journey from clinical development to the clinic

Bringing new treatments to market and delivering more precise care is challenging enough. Finding the data to empower your programs shouldn’t be. That’s why OM1 built the largest gastroenterology network in the U.S — rich with longitudinal clinical data and ready for addressing your most urgent questions.

OM1 RWD cloud

26

IDNs

2,000+

GI Specialists

Crohn’s Disease
Ulcerative colitis
• Microscopic colitis
• Celiac
• MASH (formerly known as NASH)

Sample conditions*

Every condition presents its own unique challenges and opportunities. Select one of our sample datasets above to explore some of the features.

CD patients with deep clinical data including specialist’s notes and many with extracted and calculated CDAI

8.2 yrs

Mean follow-up

&

Extracted and Calculated CDAI scores

Crohn's Disease

UC patients with deep clinical data and many with extracted and calculated Mayo scores

8.1 yrs

Mean follow-up

&

Extracted and Calculated Mayo scores

UC disease

*Data counts as of Q3 2023 ©OM1 Gastroenterology Data Specialty Area

From evidence to insights

UC use case

USE CASE
Assessing the impact of changes in the management of Ulcerative Colitis patients who have an incomplete response to TNFa Therapy

Lack of treatment options resulted in UC patients left on TNFa with dose intensification, adjunct steroids or other therapy combinations despite failing to achieve remission. How has the approval of novel therapies changed practice and patient outcomes?

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CDAI use case

USE CASE
Leveraging Observed and Calculated CDAI Scores in Patients with Crohn’s Disease to Understand Response to Therapy

The Crohn’s Disease Activity Index (CDAI) is used in clinical practice and randomized control trials (RCTs) to assess the patient’s clinical status, to select appropriate therapies, and to assess the response to treatments. Despite the value of the CDAI score, it is not frequently assessed in clinical setting.

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NASH use case

USE CASE
Identify under-and un-diagnosed MASH* patients with deep clinical data and advanced AI

Identification of both probable and confirmed non-alcoholic fatty liver disease (NAFLD) and MASH* is hampered by asymptomatic disease, under-diagnosis in routine care, lack of condition-specific treatments and poor billing code specificity. *Formerly known as NASH

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How we can help

Our specialized real world data, deep research teams, and physician experts offer you the longitudinal patient journeys and critical outcomes to enable your teams with the rapid and in-depth analyses necessary to drive your critical business objectives.

 

Fully utilize deep, clinical RWD to more efficiently design and conduct clinical trials such as seeing where unmet needs are greatest or determining which groups the protocol should be designed to enroll.

Measure key safety outcomes of interest and support regulatory requirements, such as monitoring and comparing the real-world safety profiles for patients on biologics.

Align with real world-based patient behaviors to measure adherence to novel treatment approaches for IBD-related conditions.

Develop sound evidence for payers through deep clinical and linked claims data for a more complete view of clinical outcomes and utilization. For example, to assess the cost effectiveness of early treatment interventions for CD and/or UC.

RWD can help guide planning, forecasting, and improving brand performance, such as understanding the size of the market by segment in patient subtypes that are best aligned with a brand’s positioning.

Award-Winning Research Team

Our team of award-winning researchers have authored hundreds of publications, including scientific posters, articles in peer-reviewed journals, white papers, and books.

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